Learn About CBD

What is CBD?

In the rapidly expanding world of health and wellness, CBD products have emerged as a popular natural remedy. 

With numerous brands and products flooding the market, it's essential to understand what CBD is and how to choose a reputable source. 

In this comprehensive guide, we will delve into the world of CBD and explore  MotherSage CBD products, a trusted brand known for its commitment to quality and transparency.

What is CBD?

CBD can be derived from hemp or marijuana plants. Hemp plants generally contain more CBD, while marijuana plants contain more tetrahydrocannabinol (THC).

One of hundreds of components in marijuana, CBD does not cause a "high" by itself. According to a report from the World Health Organisation, in humans, CBD exhibits no effects indicative of any abuse or dependence potential. To date, there is no evidence of public health-related problems associated with the use of pure CBD.

CBD is extracted from cannabis plants - the cannabis sativa plant family. Cannabidiol is one of over 100 cannabinoids found naturally in the cannabis sativa plant. It doesn't produce any psychoactive or intoxicating adverse effects when consumed on its own but may help reduce anxiety and pain. It is a prescription drug.


CBD comes from an oil that is extracted from the industrial hemp plant. That oil can then be taken as a liquid, or it can also be added as an ingredient in such products as gels, body oils, bath bombs, beauty products and bath salts. It should never be confused with hemp seed oil which comes from the seeds and does not contain CBD.

What is Hemp? 

The term “hemp” is used to mean cannabis that contains 0.3 percent or less THC content by dry weight.

Hemp and cannabis and at times difficult to differentiate because there’s no actual taxonomical difference between the two.

The THC level in hemp is so low, that it’s unlikely to get you high. This means that some hemp-derived CBD products containing less than 0.3% THC, which may include CBD gummies, are federally legal.

Difference Between Hemp and Marijuana Plants

The EndoCannabinoid System

The human endocannabinoid system (ECS) is a network of receptors spread throughout the body that control some of the most vital life functions including:

  • Sleep
  • Mood
  • Memory
  • Pain sensation
  • Skin and nerve function
  • Immune system
  • Appetite
  • Metabolism
  • Chronic pain
  • Inflammation and other immune system responses
  • Muscle formation
  • Stress

The human body already produces cannabinoids of its own, which are called endocannabinoids and these help to regulate the ECS. CBD and other phytocannabinoids (cannabinoids that come from plants) have the ability to interact with and stimulate our cannabinoid receptors which improve the performance of these functions.  

Homeostasis is the state of steady internal, physical, and chemical conditions maintained by all living systems and all of the above have a role to play in maintaining a balance in your body. If any of these functions are influenced by external factors (inflammation, pain, skin conditions etc) the ECS will attempt to fire up to help your body retune to a state of homeostasis.                          

How Does ECS Work?

The ECS involves three core components: endocannabinoids, receptors, and enzymes.

Endocannabinoids also called endogenous cannabinoids are molecules made by your body. They are similar to cannabinoids, but are produced by your body.

Receptors are found throughout your body. Endocannabinoids bind to them in order to signal that the ECS needs to take action. There are two main endocannabinoid receptors:

CB1 Receptors

These are mostly found in the central nervous system and are moderators of your memory, mood, motor function, perception of pain, stress response and thinking.

CB2 Receptors

These are mainly found in your peripheral nervous system, especially immune cells and control signals from your bones, immune system, respiratory tract, skeletal muscle, nervous system, and cardiovascular system as well as the moderators of inflammation.


They are responsible for breaking down endocannabinoids once they’ve carried out their function. There are two main enzymes responsible for this:

  • Fatty acid amide hydrolase, which breaks down AEA.
  • Monoacylglycerol acid lipase, which typically breaks down 2-AG.

The Evidence for Cannabidiol Health Benefits

CBD has been touted for a wide variety of health issues, but the strongest scientific evidence is for its effectiveness in treating some of the forms of epilepsy syndromes, such as Dravet syndrome and Lennox-Gastaut syndrome (LGS), which typically don't respond to antiseizure medications.

In multiple clinical studies, CBD was able to reduce the number of seizures, and, in some cases, stop them altogether. Epidiolex, which contains CBD, is the first cannabis-derived medicine approved by the FDA for these conditions.

CBD has been backed as a promising treatment for pain by organisations like the Arthritis Foundation. Research and anecdotal evidence suggest that it's also relatively widely used — a according to Arthritis Foundation, 29% of the people with arthritis that surveyed were currently using CBD to manage their symptoms. There are no safety concerns associated with CBD moderate doses so far.

CBD has been shown to have anti-inflammatory properties, and research shows that CBD has the potential beneficial for people with inflammatory skin conditions like eczema, psoriasis, acne, and psoriasis. 

Using topical CBD creams or lotions can help soothe and calm sensitive skin, reducing redness, itching, and irritation.

A CBD Body Oil can provide daily repair and protection for irritated skin — when infused with natural ingredients, a lightweight oil can soothe your skin without leaving any greasy residue behind.

CBD is also well known for its moisturising and nourishing properties, making it a great ingredient for keeping skin hydrated and healthy.

Along with regulating oil production and reducing inflammation, it helps to increase moisture retention, which means that it can keep the skin hydrated by locking in moisture.

When used in a rich formula (like this CBD Body Butter from MotherSage), it's perfect for soothing severely dehydrated skin.

While research on CBD's effects is still ongoing, some studies have shown potential benefits for its ability to alleviate pain, especially in conditions such as arthritis, multiple sclerosis, and fibromyalgia.

In addition to pain relief, CBD has also been suggested to have other potential health benefits, such as reducing anxiety and improving sleep qualityHowever, drug interactions were evident in other studies of CBD.

Visit our MotherSage blog for more CBD health benefits

What are the Effects of CBD?

CBD use carries potential side effects. Though it's often well-tolerated, CBD can cause side effects, such as dry mouth, diarrhoea, reduced appetite, drowsiness, fatigue, and signs of liver injury.

CBD can also interact with other medications you're taking, such as blood thinners, hence one is required to seek medical advice before use.

Another cause for concern is the unreliability of the purity and dosage of CBD in products. A recent study of 84 CBD products bought online showed that more than a quarter of the products contained less CBD than labelled. In addition, THC was found in 18 products.

This means there is a continued need for federal and state regulatory agencies to take steps to ensure the label accuracy of these Cannabis-derived compounds

Underlabeling is less concerning as CBD appears to neither have abuse liability nor serious adverse consequences at high doses; however, the THC content observed may be sufficient to produce intoxication or impairment, especially among children.

The FDA is Continuing to Evaluate the Regulatory Frameworks for Products Containing Cannabis and Cannabis-Derived Compounds since we also don't know the most effective dose of CBD for any particular medical condition.

Frequently Asked Questions

Is CBD Legal?

For this product to be considered legal, companies that produce this medicine must abide by the law. If the THC levels are above zero-point-three per cent, then they will not be considered as a legal product.

Are CBD Topicals Legal?

Yes, they are. Topical products containing medical cannabis are completely legal for use in the UK, Europe and the United States. In fact, many people prefer topical CBD over ingesting the oil itself due to its effectiveness when applied directly to the skin. 

Topicals also avoid the initial breakdown of the ingredients by the liver so are safer to take. They are also faster acting as they are applied directly to the affected surface and do not need to be distributed to the full body as with oral ingestion. They may help relieve pain and inflammation from arthritis, muscle soreness, and joint stiffness. 

HEMPE products include topical CBD products which are legally classified as cosmetics and fully legal for sale in the UK, EU and the US. Please do check CBD legal status if you reside outside of these areas. Ingesting CBD as a food supplement is governed using a separate set of laws.

How Can CBD be Taken?

CBD comes in many forms, including oils, extracts, capsules, patches, vapes, and topical preparations for use on skin. If you're hoping to reduce inflammation and relieve muscle and joint pain, a topical CBD-infused oil, lotion or cream – or even a bath bomb -- may be the best option. Alternatively, a CBC patch or a tincture or spray designed to be placed under the tongue allows CBD to enter the bloodstream directly.

What Makes MotherSage Products Unique?

Simply put because they work! The Unique Selling Point is the phenomenal science behind the products. They have been formulated by a team of experienced scientists from the Czech Republic. Our Czech formulators are scientists who not only have access to decades of cannabinoid research but also the world-class expertise in formulation processes and combining bioactive ingredients to deliver the most effective products. CBD is a phenomenal natural ingredient but it is only one of many reasons and ingredients that make our products so special.

MotherSage: A Trusted Source for Your CBD Skincare Products

CBD skincare products have gained significant attention in the health and wellness industry, offering potential health benefits for a wide range of individuals. 

MotherSage is a trusted brand, dedicated to providing high-quality CBD products that meet rigorous standards. With our commitment to transparency, quality assurance, and customer satisfaction, MotherSage has become a go-to choice for those seeking reliable skincare products.

As you embark on your CBD journey, remember to consult with a healthcare professional to determine the best approach for your specific needs. CBD products have the potential to enhance your skincare routine, and MotherSage is here to support you in every step you take.

    Our Story

    The MotherSage™ story started with a chance conversation. During a research trip to Prague to discuss the potential healing effects of CBD for topical pain relief, an informal chat with our scientists and formulators took place on a tea break. In their opinion, based on all the research they had seen to date, they believed that the brightest and most long-lasting future for CBD lay in SkinCare; we asked them…why?

    They noted that the two primary sources of aging and other common skin issues are free radical damage and inflammation. Based on everything they had seen and researched, they believed the natural anti-inflammatory and anti-oxidants properties of CBD made it perfectly structured to combat both. Therefore, if CBD skincare products were to be formulated properly and were to include all of the other fantastic natural oxidants and natural anti-inflammatories that nature has to offer – the resulting SkinCare products could really add something new to the market. MotherSage™ was born. 


    MotherSage™ products are formulated using over 60 years of research and data by world renowned scientists based in the Czech Republic. Research into Cannabinoids has been carried out in the Czech Republic since the 50’s. In 1955 Prof. Jan Kabelik laid the basics of the scientific research into the healing effects of cannabis, pioneering a legacy of research in the Czech Republic that continues to this day. His colleagues Prof. Zdeněk Krejčí and chemist František Šantavy were the first to discover and isolate cannabidiol acid or CBD. In 1963 Professor Šantavý published the correct absolute configuration of CBD and THC, four years ahead of Profs Raphael Mechoulam and Gaoni in Israel who independently determined and verified the findings. Many of these ground-breaking papers were published behind the Iron Curtain in the Czech language. If they had been published in English, scientific journals of their work would now be cited all over the world.

    World Class Formulations

    Today this inherited knowledge lays the foundation upon which our formulations are created. Our Czech formulators are scientists that have not only access to decades of cannabinoid research but also the world-class expertise in formulation processes and combining bioactive ingredients to deliver the most effective products.These scientists, working with skin experts and salons, over time crafted a range of five beautiful SkinCare products. We understand the prior connotations with CBD that people may have but our customers can rest assured that all of our MotherSage™ products are legally registered and regulatory compliant. CBD is a phenomenal natural ingredient but it is only one of the important reasons and ingredients that make our products so special.

    Our Multi-Award Winning Products

    MotherSage is a range of high-quality, invigorating and relaxing CBD skincare products formulated with the very best natural ingredients to help alleviate common skin ailments resulting in firmer, healthier skin.

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